Regenerative Medicine

Tapping Into the Body's Own Healing Power

Redefining Regenerative Care

for the Modern Age

Welcome to a new era of medicine—where innovation meets integrity, and healing is as individualized as the patients we serve. At Marshall Medical Group, we deliver advanced regenerative and longevity-focused care through a highly personalized, white-glove concierge model. With five premier locations and continued national expansion, our practice stands at the forefront of modern medicine—bridging science, wellness, and service excellence.


Our team of seasoned medical professionals brings decades of combined experience in procedural medicine, regenerative therapies, and complex care coordination. Each provider is extensively trained in the precise delivery of biologic treatments including Platelet-Rich Plasma (PRP), exosomes, Stem Cell Matrix products, and adipose-derived stem cells. We approach every patient encounter with clinical rigor, ethical clarity, and the utmost respect for the art of medicine.

Rooted in evidence-based practice and guided by the highest ethical standards, we believe that regenerative medicine is not just about symptom relief—it’s about redefining what it means to age well. Our treatments are carefully integrated into comprehensive wellness plans that support orthopedic recovery, sports performance, sexual health, aesthetic rejuvenation, and long-term vitality.



We view each therapy not as a standalone procedure, but as part of a greater strategy to help patients live more active, balanced, and purpose-driven lives—with extended health spans and optimized human performance. Our mission is not just to add years to your life, but life to your years.


You do not need to be a member of Marshall’s Concierge Medicine Program to receive therapy

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Why Marshall?

Wellness includes choices and activities aimed at achieving physical vitality, mental alacrity, social satisfaction, a sense of accomplishment, and personal fulfillment. Dr. Mullins has spent the last 10 years developing a unique approach to help patients live more positive lives. Lifestyle Medicine focuses on how our daily life choices affect our quality of life. Through personal accountability, introspection, perspective, coaching, structure and accountability, Marshall has helped countless patients overcome self-imposed impediments to achieving a higher meaning for their lives. This proactive approach to health replaces the antiquated, reactive manner healthcare has treated patients for millennia.

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PDGF - Platelet-Derived Growth Factor

PDGF stands for Platelet-Derived Growth Factor — a family of growth factors that play a critical role in cell growth, development, and repair, especially in blood vessels and connective tissue.

pure PDGF+ harnesses the power of nature’s most powerful growth factor for skin rejuvenation, PDGF. The benefits of platelet-derived growth factor have been extensively studied by researchers. We utilize recombinant technology to produce a pure, sterile, pharmaceutical-grade product. And unlike products jammed with additives, ariessence pure PDGF+ only contains four ingredients: water, sodium acetate, hyaluronic acid, and sh-polypeptide-59 dimer.


This product has been used successfully in the aesthetic world to regenerate connective tissue, facilitate healing after certain procedures (laser, microneedling).



In aesthetics and regenerative medicine, PDGF (Platelet-Derived Growth Factor) plays a significant role in skin rejuvenation, hair restoration, and wound healing, primarily due to its ability to stimulate collagen production, angiogenesis, and cellular repair.


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PRP – Platelet Rich Plasma

Platelet-Rich Plasma (PRP) is a natural, autologous treatment derived from your own blood. It contains a high concentration of platelets, which are rich in growth factors and signaling molecules that stimulate tissue repair, reduce inflammation, and promote collagen production.

PRP is a cornerstone of regenerative medicine and increasingly popular in aesthetics due to its ability to accelerate healing, reverse cellular aging, and enhance tissue function—all without synthetic drugs or foreign substances.


When injected into injured or aging tissue, PRP releases powerful growth factors such as:


  • PDGF (Platelet-Derived Growth Factor) – stimulates cell growth and new blood vessel formation


  • TGF-β (Transforming Growth Factor Beta) – modulates inflammation and collagen production


  • VEGF (Vascular Endothelial Growth Factor) – supports angiogenesis


  • EGF (Epidermal Growth Factor) – promotes skin regeneration and repair
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These growth factors activate local stem cells, boost cellular signaling, and support the repair of soft tissue, joints, skin, and hair follicles.

How PRP Is Prepared - (Not All PRP is Equal – In fact, the quality of the Platelet Rich Plasma Extract is highly variable between clinics offering the service. This high variability in results between clinics because of the variability of product and provider skill and experience).

A small amount of your blood is drawn in the office by the nursing staff (typically 10–60 mL).


The sample is spun in a high-speed centrifuge to separate the platelet-rich layer from red and white blood cells. Marshall utilizes the highest quality concentrating equipment available.


The concentrated PRP is extracted and re-injected or applied to targeted tissues with precision.

Depending on the indication, the PRP may be:


  • Leukocyte-rich (LR-PRP): includes white blood cells—more inflammatory, used for tendon/ligament healing
  • Leukocyte-poor (LP-PRP): filtered out—gentler, used in joints and aesthetics


We utilize PRP in Regenerative Medicine for joint pain relief, sports injuries, sexual health, aesthetics, and hair rejuvenation to:

  • Reduces inflammation and pain
  • Improve function and mobility
  • Delay or prevent joint replacement surgery
  • Improve skin elasticity and reduce the effects of aging and sun exposure
  • Stimulate hair regrowth
  • Stimulate connective tissue regrowth in the penis or vaginal area for enhanced sexual function.


Procedures are safe, pain-minimized, effective with minimal downtime.


Kenalog – Long-Acting Steroid

Kenalog is a potent synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is often used via intra-articular (joint), peri-tendinous, or intralesional injection to reduce pain and swelling caused by acute or chronic sports-related injuries.


Kenalog therapy has utility in many individuals as a component to an overall treatment program.


Kenalog Therapy can be used for the treatment of:


  • Rotator Cuff Tendinitis
  • Tennis Elbow – Epicondylitis
  • Plantar Fasciitis
  • Knee Pain caused by osteoarthritis
  • Bursitis
  • Piriformis Syndrome
  • Carpal Tunnel Syndrome
  • Thumb Pain from osteoarthritis


A skilled and experienced provider can best segregate patients into the proper treatment bucket.


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Creska™ – Stem Cell Matrix

Creska™ is derived from liposuction technology known to produce high cell viability from thoroughly screened donors and its intended use is for subcutaneous injection only where skin and fat naturally exist. Creska contains a high concentration of live, pure human derived cellular factors and proteins.


Creska™ is produced in the United States by an FDA registered lab that is also conducting multiple FDA approved clinical trials in the regenerative medicine industry.


Creska™ can be used anywhere where fat or skin naturally exists subcutaneously injected or applied topically.


Creska™ works as a stand-alone product or as a complement to many established PRP or other protocols.


Creska was created on the premise that adding younger cells and proteins to aging populations will aid the body in healing in the way nature intended it to.

Creska with PRP or PRFM: We believe that utilizing Creska as a compliment to natural autologous signaling such as platelet derived growth factors should enhance regeneration. Creska™ is an affordable Off-The-Shelf product that should be offered to many PRP and PRFM candidates.


How does Creska™ work?

Creska™ is derived from dermal adipose tissue that is classified as skin. Creska is a homologous Adipose Derived Allograft that behaves in the skin as it was naturally intended to perform. The intent is to aid in the repair, or replace damaged tissue reconstructs and replace skin tissue while supplementing natural functions. Creska™ is composed of the same cytokines and growth factors-including collagen, elastin, hyaluronic acid, proteins, nano particles, extra cellular communication mechanisms, stem cells, and human derived cellular factors that exist in tissue to help repair defects where they may exist.


Creska™ as a stand-alone product or when offered as a complement to FDA Cleared PRP and PRFM Kit applications, or other autologous treatments should work in conjunction with a person’s own cell signaling and Platelet Derived Growth Factors while adding cushioning and support for tissue, energy storage in the form of lipids and structure of the dermis with the addition of younger cellular factors. It can be used for the repair of cosmetic defects in the skin, repair of injured skin due to surface wounds, as well as provide structural components that may assist in the development of tissue structure such as filling gaps in the skin structure and hair follicles.


Creska is used in Regenerative Medicine for:


  • Hair Rejuvenation (with or without PRP)
  • Aesthetics
  • Would Repair



Exosomes

Exosomes are microscopic extracellular vesicles (30–150 nanometers in size) that are naturally released by stem cells and other regenerative cells. Think of them as messenger bubbles — carrying powerful biological signals like growth factors, proteins, cytokines, lipids, and microRNAs.


Rather than introducing whole stem cells into the body, exosomes deliver the regenerative signals those cells naturally produce — with less risk and greater consistency.


How Do Exosomes Work?


Exosomes act as cell-to-cell communicators, influencing:


  • Tissue repair
  • Inflammation modulation
  • Collagen and elastin production
  • Hair follicle stimulation
  • Immune system regulation


They do not replicate or form new tissue directly but instead activate and orchestrate your body’s own repair mechanisms.

In medical and aesthetic use, exosomes are often derived from:


  • Mesenchymal stem cells (MSCs) typically come from placental, umbilical cord, or adipose tissue
  • Adipose-derived stem cells (in-clinic processing, less common)
  • Some are acellular, purified products manufactured under GMP standards


Exosomes in Regenerative Medicine


Common Use Cases:


  • Osteoarthritis and joint pain
  • Tendon and ligament injuries
  • Neuropathic inflammation
  • Soft tissue recovery post-surgery
  • Adjunct to PRP
  • Stimulation of hair follicles to improve hair density and quality
  • Facial Rejuvenation - combined with microneedling to boost collagen, elastin, and dermal repair


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Adipose Derived Stem Cells – Harvesting and Storage

Adipose-derived stem cells (ADSCs) are multipotent mesenchymal stem cells found within fat tissue. They have become a powerful tool in regenerative medicine due to their abundance, ease of access, and ability to support healing, reduce inflammation, and stimulate tissue repair.


Unlike bone marrow-derived stem cells, ADSCs can be harvested in higher quantities with less discomfort, making them a popular source for autologous (your own) cellular therapy.

Fat tissue is one of the richest sources of regenerative cells in the body, containing:


  • Mesenchymal stem cells (MSCs)
  • Stromal vascular fraction (SVF) includes pericytes, endothelial progenitors, T-reg cells, and growth factors
  • Extracellular matrix proteins that support tissue remodeling


This cellular environment plays a vital role in modulating inflammation, supporting angiogenesis, and promoting soft tissue regeneration.


Fat Collection via Mini-Liposuction


  • A small area (commonly the abdomen, flanks, or thighs) is numbed with local anesthesia.
  • A low-volume liposuction (usually 30–100 mL of fat) is performed using a cannula.
  • This is typically done in-office with minimal discomfort and downtime.


Once collected, the adipose tissue is minimally manipulated and mechanically processed to be FDA compliant for homologous use.


Treatment Areas

Regenerative Therapies for Joint pain & Sports Injuries


Marshall specializes in high functioning men and women. As part of an active lifestyle, it is not uncommon for Men and Women to develop pain in one or multiple joints. In fact, it is rare for most men and women in their 40’s to not have at least one nagging pain syndrome – Shoulder Pain, Elbow Pain, Knee Pain, etc. The treatment of these issues is of paramount importance as maintaining an active lifestyle with resistance training, cardiovascular fitness, and the avoidance of a sedentary existence is critical to a prolonged Health Span. Regenerative Therapies are designed to support your body’s natural healing process – without relying on surgery, chronic medications, or downtime. Dr. Mullins and his highly trained providers have successfully treated thousands of patients without complications.


We have a variety of Regenerative Protocols to treat:


  • Osteoarthritis (knee, hip, hand, elbow)
  • Tendinopathies (rotator cuff, tennis elbow, Achilles)
  • Ligament Sprains or Muscle Tears
  • Overuse Syndromes
  • Sports Injuries
  • Patients hoping to delay or prevent the need for Orthopedic Surgery


Successful treatment often depends on Proper Patient Selection, Proper diagnosis, Severity of condition, Expertise of the treating Provider in treatment selection and procedural acumen.

Having pain that limits a person’s ability to function at a high level is an emergency in our opinion and we will make arrangements for you to be seen swiftly.


Marshall Provides complimentary consultations and does so to break down barriers that might prevent patients from exploring life-changing treatments.


Treatments are highly personalized and collaborative.


Hair Rejuvenation - Advanced Solutions for Thicker, Healthier Hair


Hair loss can be emotionally and physically distressing — but it doesn’t have to be permanent. Our comprehensive Hair Rejuvenation Program is designed to identify metabolic, hormonal, and lifestyle issues contributing to hair loss and a personalized plan to stimulate natural hair regrowth, improve follicle health, and restore confidence using a synergistic, evidence-based blend of regenerative medicine, advanced therapeutics therapy, and expert procedural care.


We combine cutting-edge therapies such as PRP, exosomes, and Creska stem cell matrix with topical and oral medical solutions, all performed under the comfort of a Halo Block, a regional anesthetic technique that ensures minimal discomfort during your procedures.


Regenerative Therapies

Platelet-Rich Plasma (PRP)


  • Harvested from your own blood
  • Concentrated platelets and growth factors stimulate dormant hair follicles, enhance blood flow, and improve scalp health
  • Ideal for early-stage thinning, post-COVID hair loss, and post-partum shedding


Exosomes


  • Derived from mesenchymal stem cells, these nano-vesicles carry cellular signals that direct regeneration, repair, and follicular activation
  • Potent anti-inflammatory and anti-fibrotic properties
  • Can be used as a standalone or with PRP for amplified results


Creska Stem Cell Matrix


  • A next-generation biologic allograft rich in extracellular matrix proteins, growth factors, and cytokines
  • Supports tissue remodeling, vascular health, and regenerative signaling in the scalp microenvironment


Medical Therapy: Topical & Oral Optimization

To maintain and enhance regenerative outcomes, we integrate targeted medical therapy:


  • Minoxidil (Topical or Oral): Improves follicular blood flow and anagen phase length
  • Finasteride (Topical or Oral): Blocks DHT, a hormone linked to androgenetic hair loss
  • GHK-Cu Peptide: A copper-binding peptide that promotes follicular repair, collagen synthesis, and hair growth stimulation
  • Custom Compounding Available: Our pharmacy partners can combine agents for convenience and better compliance


Comfort-Focused Procedures

All injection sessions are performed by a skilled provider using a Halo Block — a ring block of local anesthetic around the scalp that ensures a virtually pain-free experience during PRP, exosome, or Creska treatments.


Who Is This For?

  • Men and women with androgenetic alopecia (pattern baldness)
  • Individuals with thinning hair or receding hairlines
  • Patients recovering from covid and other infectious diseases or aggressive GLP-1 therapy, or hormonal imbalance frequently have hair loss.
  • Those looking for non-surgical solutions to restore natural volume and thickness


Not everyone is a candidate for this therapy and not all providers are equally proficient in recognizing those patients that are best suited for therapy. Exercise caution when interviewing providers and come prepared to ask questions to better understand a provider’s qualifications before embarking on this treatment path.

Remember, This isn’t just a cosmetic treatment — it’s a regenerative program built on science, precision, and comfort. By combining the most advanced tools in aesthetic medicine with a personalized medical approach, we help you regrow your hair, restore vitality, and feel confident again.


Sexual Health


Sexual dysfunction—whether it’s erectile dysfunction (ED) in men or arousal, lubrication, or orgasmic difficulties in women—can deeply impact quality of life, relationships, and emotional well-being. At our clinic, we offer advanced, minimally invasive regenerative therapies that target the root causes of sexual dysfunction through cellular repair, improved blood flow, and neurovascular rejuvenation.


Platelet-Rich Plasma (PRP)


PRP therapy uses your body’s own platelets, isolated from a small blood draw, to stimulate tissue regeneration. PRP contains concentrated growth factors that promote angiogenesis (new blood vessel formation), nerve regeneration, and collagen remodeling.


For Men (often called the P-Shot):

  • Injected directly into the corpus cavernosum of the penis
  • Aims to enhance erectile firmness, sensitivity, and penile vascularity
  • Can support recovery from Peyronie’s disease or after prostate treatments


For Women (often called the O-Shot):

  • Injected near the clitoral body and anterior vaginal wall (G-spot area)
  • Can improve lubrication, arousal, orgasm, and help with stress urinary incontinence\


PRP is particularly effective for patients with mild to moderate dysfunction or those seeking natural, drug-free enhancement.


Procedure Experience


All procedures are performed in-office after a regional nerve block (e.g., penile ring block or pudendal block) to ensure a virtually pain-free experience. Dr. Mullins has performed hundreds of these procedures with no complications.

Additionally, we utilize topical and local anesthetic techniques for comfort.

Typical treatment duration: 45 – 60 minutes, with minimal to no downtime.



Expected Benefits


For Men (ED):

  • Improved erectile quality and duration
  • Enhanced penile sensitivity
  • Increased response to Viagra, Cialis, and other Medications in the treatment of ED.
  • Possible penile length/girth improvement with repeat treatments


For Women (Female Sexual Dysfunction):

  • Enhanced clitoral and vaginal sensitivity
  • Improved lubrication and natural arousal
  • Stronger, more satisfying orgasms
  • Support for urinary incontinence control in perimenopausal/postmenopausal women and UTI frequency reduction



Exosomes


Exosomes are nano-sized vesicles secreted by mesenchymal stem cells. They carry powerful bioactive molecules like mRNA, cytokines, and growth factors that direct tissue healing and cellular communication.


  • Provide anti-inflammatory, pro-angiogenic, and neuroprotective effects
  • Used alone or combined with PRP for enhanced outcomes
  • May benefit men with vascular ED and women experiencing genital atrophy or loss of sensitivity due to age or hormonal decline


Exosomes are cell-free, making them a lower-risk option with high regenerative potential.


Creska Stem Cell Matrix


Creska is a proprietary human amniotic tissue allograft matrix. It contains:


  • Extracellular matrix proteins
  • Cytokines
  • Natural growth factors


These biological ingredients support:


  • Tissue remodeling
  • Collagen support
  • Microvascular regeneration


Creska can be injected in the same anatomical areas as PRP or exosomes to enhance structural repair in damaged or aging tissues. It is often reserved for patients with severe dysfunction or tissue trauma.

Aesthetics


In modern aesthetic medicine, regenerative therapies are transforming how we treat skin aging, volume loss, hair thinning, and overall tissue integrity. Rather than simply masking symptoms, advanced biologics like Platelet-Rich Plasma (PRP), Exosomes, and Creska stem cell matrix work synergistically to restore cellular vitality, improve skin architecture, and promote natural, long-lasting beauty.


PRP (Platelet-Rich Plasma)


Autologous (from the patient’s own blood), PRP delivers a high concentration of growth factors, including VEGF, PDGF, TGF-β, and EGF. It’s used to:


  • Stimulate collagen and elastin production
  • Improve skin tone, texture, and pore size
  • Support wound healing and post-procedural recovery
  • Enhance hair regrowth and sexual rejuvenation


Best paired with: microneedling, RF microneedling, facial injections, laser resurfacing, or hair restoration.


Exosomes


Derived from stem cells (commonly umbilical or mesenchymal), exosomes are nano-sized signaling vesicles loaded with mRNA, cytokines, and growth peptides that direct tissue repair and regeneration.


Benefits include:


  • Enhanced cell-to-cell communication
  • Profound anti-inflammatory and regenerative effects
  • Accelerated healing and recovery post-laser or microneedling
  • Improved pigmentation, firmness, and skin clarity


Use cases: Advanced facial rejuvenation, post-ablative laser healing, melasma, acne scarring, hair loss.


Creska (Amniotic Stem Cell Matrix)


Creska is a biologic allograft derived from human amniotic membrane, rich in:


  • Collagen
  • Extracellular matrix proteins
  • Natural growth factors and cytokines


It supports:

  • Cellular repair and tissue scaffolding
  • Reduction in inflammation
  • Structural skin regeneration


Best reserved for: patients with more severe tissue damage, deep rhytids, acne scarring, or those desiring a non-surgical facelift alternative.

Clinical Applications:


  • Face & Neck Rejuvenation Microneedling or injection-based delivery for collagen remodeling, skin laxity, and glow
  • Hair Restoration Scalp injections improve follicle density and reduce miniaturization
  • Décolleté & Hand Rejuvenation Improve crepey texture and pigmentation
  • Post-Procedure Recovery (Laser, RF, Threads) Apply topically or injected to reduce inflammation, downtime, and PIH risk
  • Sexual Wellness Enhance outcomes of P-Shot, O-Shot, and labiaplasty recovery with regenerative biologics





Combination / Adjunctive Therapy Considerations:


  • Comprehensive Biomarker Testing to evaluate for metabolic or hormonal disorders
  • Full Service, Concierge Primary Care 24/7
  • Longevity and Lifestyle-Centric Approach to all Patient Care.
  • Use of Advanced Therapeutics & Nutraceuticals, Medical Fitness Principles, Health Coaching and Personal Training.