15 Benefits of Microdosing a GLP-1

Marshall Medical Group • July 29, 2025

Microdosing GLP-1 taps into one of the body's master regulatory systems, impacting blood sugar, inflammation, the gut-brain axis, mitochondrial function, and even gene expression, all from a single peptide naturally made in your gut.



1. Supports adrenal recovery:

Reduces cortisol spikes and stabilizes energy.


2. lmproves histamine tolerance:

Lowers mast cell activation and supports microbiome rebalance.


3. Calms neuroinflammation:

Modulates microglial activity for clearer thinking.


4. Reduces anxiety:

Stimulates the vagus nerve and balances HPA axis signaling.


5. Boosts mitochondrial health:

Enhances AMPK and energy production without overstimulation.



6. Raises BDNF:

Supports brain function, focus, and neuroplasticity.



7. Regulates estrogen metabolism:

 Supports liver detox of estrogen metabolites.


8. Supports methylation:

Helps lower homocysteine and reduce methylation stress.


9. lmproves thyroid conversion:

Reduces reverse T3 and enhances T4 to T3 conversion.


10. Heals gut lining:

Reduces inflammation and improves barrier integrity.




11. Enhances nutrient absorption:

Slower transit supports better uptake of key nutrients.




12. Modulates dopamine:

 Reduces food cravings and reward-seeking behavior.




13. Lowers blood pressure:

Improves nitric oxide levels and endothelial function.




14. Reduces autoimmunity triggers:

Lowers inflammation and gut permeability.




15. Supports detox pathways:

Reduces the metabolic burden on the liver.

Schedule a Meet & Greet
By John Marshall Mullins, MD July 11, 2025
The American Health system is failing!
By Marshall Medical Group July 10, 2025
When considering Testosterone Replacement Therapy (TRT), one of the most common and anxiety-inducing questions men ask is: “Will testosterone cause prostate cancer?” This concern has deep roots in medical history, but today’s evidence paints a far more nuanced—and reassuring—picture.
By Marshall Medical Group July 10, 2025
The Latest Evidence: TRAVERSE Trial and Beyond  The most rigorous clinical trial to date—In 2023, the TRAVERSE trial (Testosterone Replacement Therapy for Assessment of Long-Term Vascular Events and Efficacy Response in Hypogonadal Men)—was designed specifically to answer the cardiovascular question.
By Marshall Medical Group May 19, 2025
Here are 10 common symptoms of low testosterone (low T) in men, which can significantly impact both physical and mental health:
By Marshall Medical Group May 19, 2025
Here are 10 potential benefits of hormonal therapy (HT) for perimenopausal women, based on current clinical evidence and expert guidelines:
By Marshall Medical Group May 19, 2025
Here are 10 evidence-based ways to add healthy decades to your life—focusing not just on longevity, but also on quality of life:
By Marshall Medical Group May 19, 2025
Bioidentical progesterone, when used appropriately and under medical supervision, does not appear to pose the same cancer risk as synthetic progestins, particularly in the context of hormone replacement therapy (HRT) for menopausal women. Here's a more detailed breakdown:
By Marshall Medical Group April 11, 2025
Optimize Your Health, Energy, and Longevity with Data-Driven Wellness In today’s fast-paced world, more people are looking for ways to optimize their health, boost energy, and extend their lifespan—not just by treating illness, but by proactively upgrading the way their body and mind function. That’s where biohacking comes in. At Marshall Medical Group, we help our patients take control of their own biology through a personalized, science-backed approach to wellness. From advanced diagnostics and targeted supplements to customized fitness and nutrition plans, biohacking is about leveraging data and innovation to help you look, feel, and perform at your best—every day.  Whether you're new to the concept or already tracking your biometrics, this guide will help you understand what biohacking is, how it works, and how concierge medicine can support you in achieving peak health.
By Marshall Medical Group April 10, 2025
As a busy executive or high-net-worth individual, your time is your most valuable asset. Between demanding work schedules, travel, and personal commitments, managing your health can often take a backseat—leading to unnecessary stress, wasted time, and frustration. Fortunately, concierge medicine offers a smarter, more efficient healthcare solution that can enhance both your work-life balance and your overall well-being. At Marshall Medical Group, we understand the unique challenges of balancing a high-powered career with personal health. With personalized care that focuses on convenience, efficiency, and high-touch service, concierge medicine provides an elevated healthcare experience tailored to your needs. Let’s explore how concierge medicine can help you reduce stress, streamline your healthcare, and ultimately reclaim your time and peace of mind.
By Marshall Medical Group April 10, 2025
For today’s business executives and frequent flyers, travel is a way of life. But with long flights, changing time zones, unfamiliar food, and varying healthcare standards around the world, staying healthy on the go can be a challenge. At Marshall Lifestyle Medicine, we offer comprehensive travel medicine services designed specifically for busy professionals. Whether you’re preparing for a trip across the country or halfway around the globe, our concierge care model ensures you have direct access to your physician —anytime, anywhere.  Let’s explore how concierge medicine can support your travel lifestyle and what steps you can take to protect your health while away from home.